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1

Phospholipase D-catalyzed transphosphatidylation in anhydrous organic solvents

Joseph O. Rich, Yuri L. Khmelnitsky

Journal:

Biotechnology and Bioengineering

Year:

2001

Language:

english

File:

PDF, 69 KB

english, 2001

2

Salts dramatically enhance activity of enzymes suspended in organic solvents

Khmelnitsky, Yuri L., Welch, Stephanie H., Clark, Douglas S., Dordick, Jonathan S.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 269 KB

english, 1994

3

Biotransformations in organic chemistry. A textbook, third edition, by Kurt Faber, Springer-Verlag, Berlin, 1997, 402 pp.

Yuri Khmelnitsky

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1997

Language:

english

File:

PDF, 51 KB

english, 1997

4

Arylsulfotransferase from Clostridium innocuum—A new enzyme catalyst for sulfation of phenol-containing compounds

Vadim V. Mozhaev, Yuri L. Khmelnitsky, Fernando Sanchez-Riera, Julie Maurina-Brunker, Reinhardt A. Rosson, Alan D. Grund

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 136 KB

english, 2002

5

Simple and efficient solid support scavenging of excess acyl donors after enzymatic acylations in organic solvents

Alexander Ya. Usyatinsky, Nadezhda M. Astakhova, Yuri L. Khmelnitsky

Journal:

Biotechnology and Bioengineering

Year:

2003

Language:

english

File:

PDF, 140 KB

english, 2003

6

Multipoint attachment to a support protects enzyme from inactivation by organic solvents: α-Chymotrypsin in aqueous solutions of alcohols and diols

Vadim V. Mozhaev, Mariya V. Sergeeva, Alla B. Belova, Yuri L. Khmelnitsky

Journal:

Biotechnology and Bioengineering

Year:

1990

Language:

english

File:

PDF, 640 KB

english, 1990

7

ChemInform Abstract: Application of Combinatorial Biocatalysis for a Unique Ring Expansion of Dihydroxymethylzearalenone.

Joseph O. Rich, Cheryl L. Budde, Luke D. McConeghey, Ian C. Cotterill, Vadim V. Mozhaev, Sheo B. Singh, Michael A. Goetz, Annie Zhao, Peter C. Michels, Yuri L. Khmelnitsky

Journal:

Year:

2009

File:

PDF, 30 KB

2009

8

Application of combinatorial biocatalysis for a unique ring expansion of dihydroxymethylzearalenone

Joseph O. Rich, Cheryl L. Budde, Luke D. McConeghey, Ian C. Cotterill, Vadim V. Mozhaev, Sheo B. Singh, Michael A. Goetz, Annie Zhao, Peter C. Michels, Yuri L. Khmelnitsky

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 882 KB

english, 2009

9

Synthesis and SAR of 4-aryl-1-(indazol-5-yl)pyridin-2(1H)ones as MCH-1 antagonists for the treatment of obesity

Mark Hadden, Dustin M. Deering, Alan J. Henderson, Matthew D. Surman, Michele Luche, Yuri Khmelnitsky, Steven Vickers, Jean Viggers, Sharon Cheetham, Peter R. Guzzo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 645 KB

english, 2010

10

Tetrahydrocarboline analogs as MCH-1 antagonists

Alan J. Henderson, Dustin Deering, James F. Grabowski, Mark Hadden, Xiaowu Jiang, Yuri Khmelnitsky, Michele Luche, Matthew D. Surman, Sharon Cheetham, Steven Vickers, Jean Viggers, Peter R. Guzzo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.70 MB

english, 2010

11

Regioselective enzymatic acylation as a tool for producing solution-phase combinatorial libraries

Vadim V. Mozhaev, Cheryl L. Budde, Joseph O. Rich, Alexander Ya. Usyatinsky, Peter C. Michels, Yuri L. Khmelnitsky, Douglas S. Clark, Jonathan S. Dordick

Journal:

Year:

1998

Language:

english

File:

PDF, 659 KB

english, 1998

12

Microwave assisted combinatorial chemistry synthesis of substituted pyridines

Ian C. Cotterill, Alexander Ya. Usyatinsky, John M. Arnold, Douglas S. Clark, Jonathan S. Dordick, Peter C. Michels, Yuri L. Khmelnitsky

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 288 KB

english, 1998

13

Biocatalytic combinatorial synthesis

John L. Krstenansky, Yuri Khmelnitsky

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 200 KB

english, 1999

14

Combinatorial biocatalysis

Joseph O Rich, Peter C Michels, Yuri L Khmelnitsky

Journal:

Current Opinion in Chemical Biology

Year:

2002

Language:

english

File:

PDF, 182 KB

english, 2002

15

Biocatalysis in nonaqueous solvents

Yuri L Khmelnitsky, Joseph O Rich

Journal:

Current Opinion in Chemical Biology

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

16

Organosoluble enzyme-polymer complexes: A novel type of biocatalyst for nonaqueous media

Alexander M. Blinkovsky, Yuri L. Khmelnitsky, Jonathan S. Dordick

Journal:

Biotechnology Techniques

Year:

1994

Language:

english

File:

PDF, 394 KB

english, 1994

17

Dry enzyme-polymer complexes: Stable organosoluble biocatalysts for nonaqueous enzymology

Alexander V. Vakurov, Alexander K. Gladilin, Andrey V. Levashov, Yuri L. Khmelnitsky

Journal:

Biotechnology Letters

Year:

1994

Language:

english

File:

PDF, 258 KB

english, 1994

18

Microwave-assisted synthesis of substituted imidazoles on a solid support under solvent-free conditions

Alexander Ya Usyatinsky, Yuri L Khmelnitsky

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

19

Aldolase stability in the presence of organic solvents

Cheryl L. Budde, Yuri L. Khmelnitsky

Journal:

Biotechnology Letters

Year:

1999

Language:

english

File:

PDF, 40 KB

english, 1999

20

Lipase-catalyzed transamidation of non-activated amides in organic solvent

Maria V. Sergeeva, Vadim V. Mozhaev, Joseph O. Rich, Yuri L. Khmelnitsky

Journal:

Biotechnology Letters

Year:

2000

Language:

english

File:

PDF, 39 KB

english, 2000

21

Oxidative enzymes possess catalytic activity in systems with ionic liquids

Glen Hinckley, Vadim V. Mozhaev, Cheryl Budde, Yuri L. Khmelnitsky

Journal:

Biotechnology Letters

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

22

Current strategies for in vitro protein glycosylation

Yuri L. Khmelnitsky

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2004

Language:

english

File:

PDF, 270 KB

english, 2004

23

Combinatorial biocatalysis: a natural approach to drug discovery

Peter C Michels, Yuri L Khmelnitsky, Jonathan S Dordick, Douglas S Clark

Journal:

Trends in Biotechnology

Year:

1998

Language:

english

File:

PDF, 116 KB

english, 1998

24

Catalysis by amine oxidases in nonaqueous media

Jennifer A Chaplin, Cheryl L Budde, Yuri L Khmelnitsky

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2001

Language:

english

File:

PDF, 217 KB

english, 2001

25

Enzymatic nitration of phenols

Cheryl L Budde, Andreas Beyer, Inmar Z Munir, Jonathan S Dordick, Yuri L Khmelnitsky

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2001

Language:

english

File:

PDF, 283 KB

english, 2001

26

Micellar enzymology

Karel MARTINEK, Andrey V. LEVASHOV, Natalya KLYACHKO, Yuri L. KHMELNITSKI, Ilya V. BEREZIN

Journal:

Year:

1986

Language:

english

File:

PDF, 1.79 MB

english, 1986

27

Detergentless microemulsions as media for enzymatic reactions : Cholesterol oxidation catalyzed by cholesterol oxidase

Yuri L. KHMELNITSKY, Riet HILHORST, Cees VERGER

Journal:

Year:

1988

Language:

english

File:

PDF, 704 KB

english, 1988

28

Catalytic activity and denaturation of enzymes in water/organic cosolvent mixtures : α-Chymotrypsin and laccase in mixed water/alcohol, water/glycol and water/formamide solvents

Vadim V. MOZHAEV, Yuri L. KHMELNITSKY, Mariya V. SERGEEVA, Alla B. BELOVA, Nataliya L. KLYACHKO, Andrey V. LEVASHOV, Karel MARTINEK

Journal:

Year:

1989

Language:

english

File:

PDF, 625 KB

english, 1989

29

Kinetic theory of enzymatic reactions in reversed micellar systems : Application of the pseudophase approach for partitioning substrates

Yuri L. KHMELNITSKY, Irina N. NEVEROVA, Vyacheslav I. POLYAKOV, Valeri Ya. GRINBERG, Andrei V. LEVASHOV, Karel MARTINEK

Journal:

Year:

1990

Language:

english

File:

PDF, 536 KB

english, 1990

30

Denaturation capacity: a new quantitative criterion for selection of organic solvents as reaction media in biocatalysis

Yuri L. KHMELNITSKY, Vadim V. MOZHAEV, Alla B. BELOVA, Maria V. SERGEEVA, Karel MARTINEK

Journal:

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

31

The effect of water content and nature of organic solvent on enzyme activity in low-water media : A quantitative description

Saskia H. M. van ERP, Elvira O. KAMENSKAYA, Yuri L. KHMELNITSKY

Journal:

Year:

1991

Language:

english

File:

PDF, 553 KB

english, 1991

32

Reversed micelles of polymeric surfactants in nonpolar organic solvents : A new microheterogeneous medium for enzymatic reactions

Yuri L. KHMELNITSKY, Alexandr K. GLADILIN, Valentin L. ROUBAILO, Karel MARTINEK, Andrey V. LEVASHOV

Journal:

Year:

1992

Language:

english

File:

PDF, 779 KB

english, 1992

33

Catalysis by α-chymotrypsin entrapped into surface-modified polymeric nanogranules in organic solvent

Yuri L. KHMELNITSKY, Irina N. NEVEROVA, Alexey V. GEDROVICH, Vladimir A. POLYAKOV, Andrey V. LEVASHOV, Karel MARTINEK

Journal:

Year:

1992

Language:

english

File:

PDF, 783 KB

english, 1992

34

Dissociation of lactate dehydrogenase in aqueous and reversed micellar solutions : A time-resolved polarized fluorescence study

Yuri L. KHMELNITSKY, Arie van HOEK, Cees VEEGER, Antonie J. W. G. VISSER

Journal:

Year:

1993

Language:

english

File:

PDF, 556 KB

english, 1993

35

Enzyme inactivation and protection during entrapment in reversed micelles

Yuri L. KHMELNITSKY, Riet HILHORST, Antonie J. W. G. VISSER, Cees VEEGER

Journal:

Year:

1993

Language:

english

File:

PDF, 583 KB

english, 1993

36

Relationship between surface hydrophilicity of a protein and its stability against denaturation by organic solvents

Yuri L. Khmelnitsky, Alla B. Belova, Andrey V. Levashov, Vadim V. Mozhaev

Journal:

Year:

1991

Language:

english

File:

PDF, 328 KB

english, 1991

37

The evolution of biotransformation technologies

Jonathan S Dordick, Yuri L Khmelnitsky, Maria V Sergeeva

Journal:

Current Opinion in Microbiology

Year:

1998

Language:

english

File:

PDF, 682 KB

english, 1998

38

Detergentless microemulsions as media for enzymatic reactions: spectroscopic and ultracentrifugation studies

Khmelnitsky, Yuri L., Van Hoek, Arie, Veeger, Cees, Visser, Antonie J. W. G.

Journal:

Journal of Physical Chemistry

Year:

1989

Language:

english

File:

PDF, 949 KB

english, 1989

39

5-(Pyridinon-1-yl)indazoles and 5-(furopyridinon-5-yl)indazoles as MCH-1 antagonists

Matthew D. Surman, Emily E. Freeman, James F. Grabowski, Mark Hadden, Alan J. Henderson, Guowei Jiang, Xiaowu (May) Jiang, Michele Luche, Yuri Khmelnitsky, Steven Vickers, Jean Viggers, Sharon Cheetha

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

40

Molecular Imprinting of Enzymes with Water-Insoluble Ligands for Nonaqueous Biocatalysis

Rich, Joseph O., Mozhaev, Vadim V., Dordick, Jonathan S., Clark, Douglas S., Khmelnitsky, Yuri L.

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 31 KB

english, 2002

41

Improved Synthesis of the C16–C20 Segment of Resolvin E1 Using Enantioselective Ketone Reduction and Lipase-Catalyzed Resolution

Amin, Rasidul, Chen, Jian-Xie, Cotterill, Ian C., Emrich, Daniel, Ganley, Daniel, Khmelnitsky, Yuri L., McLaws, Mark D., Michels, Peter C., Schwartz, C. Eric, Thomas, Deb, Yan, Jun, Yang, Qiang

Journal:

Organic Process Research & Development

Year:

2013

Language:

english

File:

PDF, 306 KB

english, 2013

42

In vitro biosynthesis, isolation, and identification of predominant metabolites of 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one (RVX-208)

Khmelnitsky, Yuri L., Mozhaev, Vadim V., Cotterill, Ian C., Michels, Peter C., Boudjabi, Sihem, Khlebnikov, Vladimir, Madhava Reddy, M., Wagner, Gregory S., Hansen, Henrik C.

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

43

The design and synthesis of novel SGLT2 inhibitors: C-glycosides with benzyltriazolopyridinone and phenylhydantoin as the aglycone moieties

Guo, Cheng, Hu, Min, DeOrazio, Russell J., Usyatinsky, Alexander, Fitzpatrick, Kevin, Zhang, Zhenjun, Maeng, Jun-Ho, Kitchen, Douglas B., Tom, Susan, Luche, Michele, Khmelnitsky, Yuri, Mhyre, Andrew J

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 400 KB

english, 2014

44

Synthesis of Water-Soluble Paclitaxel Derivatives by Enzymatic Acylation

Khmelnitsky, Yuri L., Budde, Cheryl, Arnold, J. Michael, Usyatinsky, Alexander, Clark, Douglas S., Dordick, Jonathan S.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 96 KB

english, 1997

45

Suspended and Immobilized Chymotrypsin in Organic Media: Structure-Function Relationships Revealed by Electron Spin Resonance Spectroscopy

Suzawa, Valerie M., Khmelnitsky, Yuri L., Giarto, Leonard, Dordick, Jonathan S., Clark, Douglas S.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 701 KB

english, 1995

46

Biocatalytic Resolution of Bis-tetrahydrofuran Alcohol

Khmelnitsky, Yuri L., Michels, Peter C., Cotterill, Ian C., Eissenstat, Michael, Sunku, Venkataiah, Veeramaneni, Venugopal R., Cittineni, Hariprasad, Kotha, Gopal R., Talasani, Shyamsunder R., Ramanat

Journal:

Organic Process Research & Development

Year:

2011

Language:

english

File:

PDF, 324 KB

english, 2011

47

Novel Oxidation of Cyclosporin A: Preparation of Cyclosporin Methyl Vinyl Ketone (Cs-MVK)

Yang, Zhicai, Pattamana, Kevin, Molino, Bruce, Haydar, Simon, Cao, Yeyu, Bois, Frederic, Maeng, Jun-Ho, Hemenway, Michael, Rich, Joseph, Khmelnitsky, Yuri, Friedrich, Thomas, Peace, Denise, Michels, P

Journal:

Year:

2009

Language:

english

File:

PDF, 158 KB

english, 2009

48

Ambient Condition Production of High Quality Reduced Graphene Oxide

Evlashin, Stanislav A., Svyakhovskiy, Sergey E., Fedorov, Fedor S., Mankelevich, Yuri A., Dyakonov, Pavel V., Minaev, Nikita V., Dagesyan, Sarkis A., Maslakov, Konstantin I., Khmelnitsky, Roman A., Su

Journal:

Advanced Materials Interfaces

Year:

2018

Language:

english

File:

PDF, 3.24 MB

english, 2018

49

Ambient Condition Production of High Quality Reduced Graphene Oxide

Evlashin, Stanislav A., Svyakhovskiy, Sergey E., Fedorov, Fedor S., Mankelevich, Yuri A., Dyakonov, Pavel V., Minaev, Nikita V., Dagesyan, Sarkis A., Maslakov, Konstantin I., Khmelnitsky, Roman A., Su

Journal:

Advanced Materials Interfaces

Year:

2018

File:

PDF, 1.38 MB

2018

50

Ambient Condition Production of High Quality Reduced Graphene Oxide

Evlashin, Stanislav A., Svyakhovskiy, Sergey E., Fedorov, Fedor S., Mankelevich, Yuri A., Dyakonov, Pavel V., Minaev, Nikita V., Dagesyan, Sarkis A., Maslakov, Konstantin I., Khmelnitsky, Roman A., Su

Journal:

Advanced Materials Interfaces

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018